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Heart Medication Summary |
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This page
lists the side-effects of certain |
Vaughn's
Summaries |
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448-768 |
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260 |
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2. Antiarrhythmics (some of which are also #1. above) |
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Class 1 |
Sodium Channel Blockers - Rhythm? |
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Class 2 |
Beta Blockers - Rate? |
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Class 3 |
Potassium Channel Blockers - Rhythm? |
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Class 4 |
Calcium Channel Blockers - Rate? |
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chloestyramine, statins |
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aspirin, aprotinin, clopidogrel, |
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Plavix
Class Action Lawsuits |
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5. Rate Control |
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digitalis preparations |
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6. Vasodilators |
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nitroglycerin, etc. |
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Bextra (NSAID- cox-2 inhibitor) |
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Heart Drug Sales History by Year - Disclaimer Top selling cardiac drugs are shown in BOLD PINK. This list is Alphabetical by generic name. If you are taking a drug in the "Brand Name" column, ask your doctor if the cheaper "generic name" is available. |
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100 |
280 - 768 |
50 |
50 |
288 |
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ACE Inhibitors -
Angiotensin-Converting Enzyme Inhibition |
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generic name |
Brand Name |
mg |
per |
Action/ Note |
Side Effects |
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benazepril |
Lotensin |
10 20 40 |
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#135 Selling Drug 2003 |
Cough, headache, dizziness,
drowsiness, |
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captopril |
Capoten |
25 50 100 |
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- |
Dizziness or lightheadedness, salty or
metallic taste, or decreased ability to taste, cough, sore
throat, fever, mouth sores, unusual bruising, fast
heartbeat, excessive tiredness |
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cartopril |
(spanish) |
25 |
- |
- |
weakness or dizziness |
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enalapril |
Vasotec |
5 10 20 |
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Merck |
Cough, dizziness, rash, weakness, |
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fosinopril |
Monopril |
20 40 |
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#128 Selling Drug 2003 |
Dizziness, cough, upset stomach,
vomiting, diarrhea, headache, xcessive tiredness,
weakness, |
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lisinopril |
Prinivil |
5 10 20 30 40 |
- |
Generic was #149 Selling Drug 2004 |
Cough, dizziness, headache,
excessive tiredness, upset stomach, diarrhea, weakness,
sneezing, runny nose, decrease in sexual ability, rash, |
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moexipril |
Univasc |
15 |
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- |
agranulocytosis, angioedema, fetal mortality, hepatic failure, hypotension, neutropenia, |
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quinapril |
Accupril |
10 20 40 |
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- |
agranulocytosis, angioedema, fetal mortality, hepatic failure, hypotension, neutropenia, |
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ramipril |
Altace |
2.5 5 10 |
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#56 Selling Drug 2007 |
Headache, dizziness, cough, upset
stomach, vomiting, excessive tiredness, weakness, |
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trandolapril |
Mavik |
2 4 |
- |
- |
Cough, dizziness, muscle pain, |
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Combos |
Combination of 2 drugs |
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benazepril |
Lotrel |
5-10 5-20 5-40 10-20 10-40 |
- |
Novartis |
- |
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Alpha Agonists |
(norepinephren release - decrease adrenergic tone) |
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generic name |
Brand Name |
mg |
per |
Action/ Note |
Side Effects |
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clonidine |
Catapres |
0.200 0.300 |
- |
#165 Selling Drug 2007 |
I take the
0.2mg daily. I have reservations, but it does lower the heck
out of my BP. Rapid withdrawal can result in Rebound
Hypertension, and |
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guanabenz |
Wytensin |
8 16 |
- |
- |
While taking - |
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guanethidine |
Ismelin |
25 |
- |
- |
Drowsiness, dizziness, tiredness,
headache, confusion, decreased sexual ability, upset
stomach, loss of appetite, gas, constipation, vomiting, dry
mouth, frequent urination, muscle pain, depression,
difficulty sleeping |
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guanfacine |
Tenex |
2 3 |
- |
- |
Dry mouth, drowsiness, dizziness,
constipation, tiredness, headache, decreased sexual ability,
upset stomach, vomiting |
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methyldopa |
Aldomet |
250 500 |
- |
- |
Drowsiness, headache, muscle weakness,
swollen ankles or feet, upset stomach, vomiting, diarrhea,
gas, dry mouth, rash |
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monoxidine |
Physiotens |
300 400 |
- |
- |
- |
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tizanidine HCl |
Zanaflex |
4 6 |
- |
- |
Dizziness, upset stomach, vomiting,
tingling sensation in the arms, legs, hands, and feet, dry
mouth, increased muscle spasms |
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- |
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generic name |
Brand Name |
mg |
per |
Action/ Note |
Side Effects |
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STATINS |
- |
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atorvastatin |
Lipitor |
20 40 80 |
- |
#1 Selling Drug 2003, 2004, 2005, 2006, 2007 |
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cerivastatin |
Baycol |
- |
- |
Recalled 2001 |
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cholestyramine |
Questran |
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- |
- |
- |
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ezetimibe (Zetia)
and simvastatin (Zocor) |
Vytorin |
10-20 10-40 10-80 |
- |
#12 Selling Drug 2007 |
- |
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fluvastatin |
Lescol |
40 80 |
- |
Novartis |
- |
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lovastatin |
Mevacor |
20 40 |
- |
Merck |
Constipation |
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pravastatin |
Mevalotin |
20 40 |
- |
- |
- |
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rosuvastatin |
Crestor |
10 20 40 |
- |
#23 Selling Drug 2007 |
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simvastatin |
Zocor |
40, 80 |
- |
#8 Selling Drug 2006 |
- |
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- |
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colestipol |
Colestid |
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- |
- |
Chest pain, angina, and tachycardia have been reported. |
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ezetimibe |
Zetia |
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- |
#21 Selling Drug 2007 |
Severe allergic reaction |
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fenofibrate |
Tricor |
134 200 |
- |
#30 Selling Drug 2007 |
- |
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niacin |
Niaspan |
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- |
#70 Selling Drug
2007 |
- |
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- |
. |
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Blood Thinners |
(to prevent stroke) |
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generic name |
Brand Name |
mg |
per |
Action/ Note |
Side Effects |
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Bayer |
325 |
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- |
Increased bleeding risk |
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Trasylol |
- |
- |
hospital use |
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Plavix |
300 |
- |
#5 Selling Drug 2007 |
Plavix
Class Action |
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150 |
- |
new 2011 |
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Lovenox |
- |
- |
#53 Selling Drug 2007 |
- |
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Calciparine |
- |
- |
hospital use |
- |
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Xarelto |
- |
- |
clotting protein blocker |
- |
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warfarin |
Coumadin |
2 2.5 3 4 5 6 7.5 10 |
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Bristol-Myers Squibb
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Headache, upset stomach, diarrhea, fever,
skin rash, |
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- |
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Digitalis Preparations |
(Pulse Rate Control) |
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generic name |
Brand Name |
mg |
per |
Action/ Note |
Side Effects |
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digoxin |
Lanoxin |
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- |
Loss of appetite |
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Digitran |
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- |
- |
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digitoxin |
Crystodigin |
0.20 |
- |
- |
- |
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- |
. |
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Vasodilators |
(Expand blood vessels) |
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generic name |
Brand Name |
mg |
per |
Action/ Note |
Side Effects |
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hydralazine |
Apresoline |
25 50 100 |
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Novartis |
Flushing (feeling of warmth), headache,
upset stomach, vomiting, loss of appetite, diarrhea,
constipation, eye tearing, stuffy nose, rash, |
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isosorbide dinitrate |
Isordil |
10 20 30 40 |
- |
Wyeth |
Headache, rash, dizziness, upset stomach,
headache, flushing (feeling of warmth), |
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isosorbide mononitrate |
Imdur |
10 |
- |
ESP Pharma. |
- |
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nitroglycerin |
Nitrobid |
6.5 9 |
- |
Aventis |
Headache, rash, dizziness, upset stomach,
flushing (feeling of warmth), |
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nitroglycerin |
NitroQuick |
0.4 0.6 |
- |
Phizer |
- |
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- |
. |
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celecoxib |
Celebrex |
- |
- |
Heart Attack |
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rofecoxib |
Vioxx |
- |
- |
Recalled 2004 |
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valdecoxib |
Bextra |
- |
- |
Recalled 2005 |
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2003, 2004, 2005, 2006 and 2007 Top U.S. Heart Drug Sales List - Comparison Chart |
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Sales Rank |
Sales Rank |
Sales Rank |
Sales Rank |
Sales Rank |
Listed by 2007 Sales |
2007 U.S. Sales |
Primary Use |
Company |
. |
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Lipitor |
$6,165M |
cholesterol |
Pfizer |
Lipitor Rules! |
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7 |
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Plavix |
$3,082M |
anticoagulant |
Bristol-Myers Squibb |
Big seller |
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>200 |
>200 |
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Vytorin |
$1,938 M |
cholesterol |
Merck |
Rapid growth |
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126 |
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Zetia |
$1,405 M |
cholesterol |
Merck |
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>200 |
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Crestor |
$1,367 M |
cholesterol |
AstraZeneca |
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Diovan |
$1,117 M |
hypertension - AIIRA |
Novartis |
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Tricor |
$1,106 M |
cholesterol |
Abbott Labs |
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Diovan HCT |
$1,051 M |
Combo - AIIRA + HCTZ |
Novartis |
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Coreg |
$1,013 M |
Beta blocker |
GlaxoSmithKline |
Topped out |
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Lotrel |
$ 908 M |
Combo - ACE In. + CCB |
Novartis |
Declining fast |
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Toprol XL |
$ 888 M |
hypertension - BB |
Astrazeneca |
Declining fast |
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10 |
9 |
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Norvasc |
$ 749 M |
hypertension - CCB |
Pfizer |
Dropped like a rock |
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Lovenox |
$ 746 M |
anticoagulant |
Sanofi-Aventis |
Slow growth |
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Altace |
$ 710 M |
hypertension - ACE In. |
Wyeth |
Topped out |
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Cozaar |
$ 652 M |
hypertension - AIIRA |
Merck |
Topped out |
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163 |
122 |
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Niaspan |
$ 546 M |
cholesterol |
Kos Pharma. |
Growing |
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101 |
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Hyzaar |
$ 499 M |
hypertension |
Merck |
Topped out |
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>200 |
>200 |
131 |
104 |
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Benicar HCT |
$ 414 M |
Combo - AIIRA + HCTZ |
Sankyo Pharma. |
Slow growth |
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>200 |
>200 |
197 |
121 |
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Caduet |
$ 388 M |
Combo - chol. + CCB |
Pfizer |
Growing |
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119 |
113 |
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Avapro |
$ 384 M |
hypertension - AIIRA |
Bristol-Myers Squibb |
Waning |
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>200 |
>200 |
126 |
108 |
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Benicar |
$ 369 M |
hypertension - AIIRA |
Sankyo Pharma. |
Slow growth |
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4 |
5 |
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$ 353 M |
anemia |
J & J |
Whoops! Gone bad. |
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>200 |
180 |
116 |
111 |
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Avalide |
$ 328 M |
Combo - AIIRA + HCTZ |
Bristol-Myers Squibb |
Slow growth |
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>200 |
>200 |
167 |
160 |
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$ 187 M |
hypertension - AA |
Boehringer-Ingelheim |
Topped out |
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>200 |
>200 |
>200 |
>200 |
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Welchol |
$ 161 M |
cholesterol |
Sankyo Pharma. |
New |
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>200 |
>200 |
183 |
181 |
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Atacand |
$ 160 M |
hypertension - AIIRA |
Astrazeneca |
Slow growth |
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108 |
123 |
137 |
154 |
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Coumadin Tabs |
$ 160 M |
anticoagulant |
Bristol-Myers Squibb |
Going bad |
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>200 |
>200 |
>200 |
>200 |
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Micardis |
$ 148 M |
hypertension - AIIRA |
Boehringer-Ingelheim |
New |
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$ 144 M |
hypertension - BB |
GlaxoSmithKline |
Whoops! Gone bad. |
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>200 |
199 |
138 |
151 |
>200 |
? |
cholesterol |
Abbott Labs |
These drugs have fallen off the map. |
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2 |
2 |
4 |
8 |
>200 |
? |
cholesterol |
Merck |
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>200 |
? |
cholesterol |
Bristol-Myers Squibb |
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187 |
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>200 |
? |
anemia |
Amgen |
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9 |
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>200 |
>200 |
>200 |
? |
anemia |
Amgen |
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158 |
149 |
>200 |
>200 |
>200 |
lisinopril |
? |
hypertension - ACE In. |
Teva Pharma. |
Wicked cough |
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135 |
>200 |
>200 |
>200 |
>200 |
Lotensin |
? |
hypertension - ACE In. |
Novartis |
Cough |
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128 |
>200 |
>200 |
>200 |
>200 |
Monopril |
? |
hypertension - ACE In. |
Bristol-Myers Squibb |
Cough |
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Red = Sales drop from
previous year |
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40 |
40 |
40 |
40 |
40 |
80 |
60 |
160 - 768 |
120 |
150 |
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DISCLAIMER |
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Vaughn's Summaries ©2004-2011 Vaughn Aubuchon ... All Rights Reserved www.vaughns-1-pagers.com This Vaughns Summaries Human Heart Drugs Summary web page was updated on 2012-01-30. |