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Medicine Summaries
Prescription Drugs

Prescription Heart Drugs
Heart Medication Summary

(This page is not intended
for small screens.)

by Vaughn Aubuchon

This page lists the side-effects of certain prescription heart drugs. Here is a summary listing of current human heart medications by class, with generic names, brand names, and some side effects. Class action lawsuits are also referred to. This page is offered as a starting point for further research.



Sometimes they give you the Brand Name.
Sometimes they give you the generic name.
Sometimes they give you the Other Brand name.
Sometimes they Capitalize the generic name.
Sometimes they don't capitalize the brand name.
Drive you nuts? Me too. I hope the list below helps.



.
TOP 4 WORST Heart Medications
Drug
(generic version)
Class

.
Problems

1. lisinopril

ACE Inhibitor

Wicked COUGH
NEVER AGAIN for me.
Made from pit viper venom.

2. metoprolol

Beta blocker

WEAKNESS, depression - TERRIBLE
NEVER AGAIN for me.
Empties your energy.

3. amlodipine

CCB

Ankle SWELLING - TERRIBLE
NEVER AGAIN for me.
Could NOT put on Ugg boots.

4. HCTZ

Diuretic

Sucks you dry - TERRIBLE
NEVER AGAIN for me.
Drains you of potassium.

Be advised that other drugs of the same class
can also have similar devastating effects.


     Drug Class

# of Drugs in Class
# of gen-
erics

.


Legal Problems

1. Hypertension - Blood Pressure Reduction

Class 1.

ACE Inhibitors

10
7

ACE Inhibitor Birth Defects

Class 2.

Alpha Agonists

7
2

Class 3.

Alpha Blockers

4
3

Cardura Class Action Lawsuit

Class 4.

Angiotensin II Receptor Blockers

6
0

Class 5.

Diuretics

12
8

Class 6.

Renin Blockers

1
0

-

2. Antiarrhythmics (half of which are also #1. above)

Class 1 

Sodium Channel Blockers - A, B, C

9
0

-

Class 2 

Beta Blockers - Rate?

15
7

Coreg Class Action

Class 3 

Potassium Channel Blockers - Rhythm?

5
0

Amiodarone Class Action

Class 4 

Calcium Channel Blockers - Rate?

9
2

Cardizem Class Action

-

3. Cholesterol Lowering

chloestyramine, statins

8
2

Statin Class Action

-

4. Blood Thinners - Anticoagulants

aspirin, aprotinin, clopidogrel,
enoxaparin, heparin, warfarin
dabigatran etexilate

7
1

Plavix Class Action

Trasylol Class Action

Pradaxa

-

5. Rate Control

digitalis preparations

2
1

-

6. Vasodilators

nitroglycerin, etc.

5
5

-

7. Non-heart Drugs that Cause Heart Attacks

Bextra (NSAID- cox-2 inhibitor)
Celebrex (NSAID- cox-2 inhibitor)
Vioxx (NSAID- cox-2 inhibitor)

-
-

Bextra Recall

Celebrex Recall

Vioxx Recall

.
Heart Drug Sales History by Year - Disclaimer

Top selling cardiac drugs are shown in BOLD PINK.
This list is Alphabetical by generic name.
If you are taking a drug in the "Brand Name" column,
ask your doctor if the cheaper "generic name" is available.

60

250

40

40

200 - 600


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1. Blood Pressure Reduction
    Hypertension Treatment

1. ACE Inhibitors - Angiotensin-Converting Enzyme Inhibition
(ACE Inhibitors are derived from the venom of the Brazilian Pit Viper.)

ACE Inhibitor Birth Defects

generic name
( -pril)

Brand Name

Typ.
mg

Action/ Note

Side Effects

benazepril

(generic available)

half-life= 10 hours

Lotensin

5
10
20
40

#135 Selling Drug 2003

Cough, headache, dizziness, drowsiness,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, hoarseness,
difficulty breathing or swallowing,
lightheadedness, fainting,
rash, yellowing of the skin or eyes,
fever, sore throat, chills, and other signs of infection

captopril

(generic available)

half-life= 2 hours

Capoten

12.5
25
50
100

-

Dizziness or lightheadedness, salty or metallic taste, or decreased ability to taste, cough, sore throat, fever, mouth sores, unusual bruising, fast heartbeat, excessive tiredness

If you experience any of the following symptoms, call your doctor immediately:
Chest pain,
swelling of the face, eyes, lips, tongue, arms, or legs,
difficulty breathing or swallowing,
fainting, rash

cartopril

 (spanish)

12
25

-

weakness or dizziness

enalapril

(generic available)

half-life= 11 hours

Vasotec
Enaladex
Vaseretic

2.5
5
10
20

Merck

Merck

Cough, dizziness, rash, weakness,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, hoarseness,
difficulty breathing or swallowing,
yellowing of the skin or eyes,
fever, sore throat, chills, and other signs of infection,
lightheadedness, fainting

fosinopril

(generic available)

half-life= 12 hours

Monopril

10
20
40

Bristol-Mey.

Sales Momentum 2003 - #128
2004 - Gone!
2005 - Gone!
2006 - Gone!
2007 - Gone!
2008 - Gone!
2009 - Gone!
2010 - Gone!

Dizziness, cough, upset stomach, vomiting, diarrhea, headache, xcessive tiredness, weakness,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, hoarseness,
difficulty breathing or swallowing,
yellowing of the skin or eyes,
fever, sore throat,
chills, and other signs of infection,
lightheadedness, fainting

lisinopril

(generic available)

half-life= 12 hours

Prinivil
Tensopril
Zestril
Hipril

 2.5
5
10
20
30
40

Teva

Sales Momentum
2003 - #158
2004 - #149
2005 - Gone!
2006 - Gone!
2007 - Gone!
2008 - Gone!
2009 - Gone!
2010 - Gone!

1st Worst Heart Drug.
COUGH
, dizziness, headache, excessive tiredness, upset stomach, diarrhea, weakness, sneezing, runny nose, decrease in sexual ability, rash,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, hoarseness,
difficulty breathing or swallowing,
fever, sore throat, chills, and other signs of infection,
yellowing of the skin or eyes,
lightheadedness, fainting, chest pain

moexipril
half-life= 1 hour

Univasc

7.5
15

-

agranulocytosis, angioedema, fetal mortality, hepatic failure, hypotension, neutropenia,

quinapril

(generic available)

half-life= 2 hours

Accupril

5
10
20
40

 -

agranulocytosis, angioedema, fetal mortality, hepatic failure, hypotension, neutropenia,

ramipril

half-life= 3 hours

Altace


Delix
Tritace

1.25
2.5
5
10

Sanofi-Aventis

Sales Momentum
2006 - #50
2007 - #56
2008 - #165
2009 - Gone!
2010 - Gone!
2011 - Gone!

Headache, dizziness, cough, upset stomach, vomiting, excessive tiredness, weakness,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, hoarseness,
difficulty breathing or swallowing,
yellowing of the skin or eyes,
fever, sore throat, chills, and other signs of infection,
lightheadedness, fainting

trandolapril

(generic available)

half-life= 10 hours

Mavik

1
2
4

Cough, dizziness, muscle pain,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, hoarseness,
difficulty breathing or swallowing,
yellowing of the skin or eyes,
fever, sore throat, chills, and other signs of infection,
lightheadedness, fainting

Combos

Combination of 2 drugs

benazepril
amlodipine

Lotrel

2.5-10
5-10
5-20
5-40
10-20
10-40

Novartis

Sales Momentum
2006 - #28
2007 - #42
2008 - Gone!
2009 - #110
2010 - #106
2011 - Gone!

-

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Hypertension
2. Alpha Agonists

(norepinephren release - decrease adrenergic tone)

generic name
( -ine)

Brand Name

Typ.
mg

Action/ Note

Side Effects

clonidine

(generic available)

half-life= 14 hours

Catapres
Kapvay
Nexicion

0.100
0.200
0.300 

Sales Momentum
2005 - #167
2006 - #160
2007 - #165
2008 - #157
2009 - #172
2010 - Gone!
2011 - Gone!

(The author used to take the 0.2mg TID. I had reservations, but it worked well for me.)
Dry mouth, drowsiness, dizziness, constipation, tiredness, headache, nervousness, decreased sexual ability, upset stomach, vomiting, rash

If you experience any of the following symptoms, call your doctor immediately:
Fainting,
increased or decreased heartbeat,
irregular heartbeat,
swollen ankles or feet,

Rapid withdrawal can result in Rebound Hypertension, and
hypertensive crisis - an increase in blood pressure that can be FAR greater than the original high blood pressure. If you miss a pill or two, the rebound occurs immediately.

guanabenz

half-life= 6 hours

Wytensin

4
8
16

 -

While taking -
Dizziness; drowsiness; dryness of mouth; weakness, decreased sexual ability; headache; nausea
When you stop -
Anxiety or tenseness; chest pain; fast or irregular heartbeat; headache ; increased salivation; increase in sweating; nausea or vomiting; nervousness or restlessness; shaking or trembling of hands or fingers; stomach cramps ; trouble in sleeping

guanethidine

half-life= 1.5 days

Ismelin

10
25

 -

Drowsiness, dizziness, tiredness, headache, confusion, decreased sexual ability, upset stomach, loss of appetite, gas, constipation, vomiting, dry mouth, frequent urination, muscle pain, depression, difficulty sleeping

If you experience any of the following symptoms, call your doctor immediately:
Severe diarrhea, fainting, fever,
increased or decreased heartbeat,
irregular heartbeat,
chest pain,
swollen ankles or feet,
shortness of breath

guanfacine

(generic available)

half-life= 17 hours

Tenex
Intuniv (ER)

1
2
3

 -

Dry mouth, drowsiness, dizziness, constipation, tiredness, headache, decreased sexual ability, upset stomach, vomiting

If you experience any of the following symptoms, call your doctor immediately:
Fainting,
increased or decreased heartbeat,
irregular heartbeat
swollen ankles or feet

methyldopa

half-life= 105 minutes

Aldomet
Aldoril
Dopamet
Dopegyt

125
250
500

Drowsiness, headache, muscle weakness, swollen ankles or feet, upset stomach, vomiting, diarrhea, gas, dry mouth, rash

If you experience any of the following symptoms, call your doctor immediately:
Unexplained fever, extreme tiredness,
yellowing of the skin or eyes

monoxidine
half-life= 2.2 hours

Physiotens

200
300
400

 -

 -

tizanidine HCl

half-life= 2.5 hours

Zanaflex
Sirdalud

2
4
6

 -

Dizziness, upset stomach, vomiting, tingling sensation in the arms, legs, hands, and feet, dry mouth, increased muscle spasms

If you experience either of the following symptoms, call your doctor immediately:
Yellowing of the skin or eyes,
unexplained flu-like symptoms

150

70

50

120

300 - 690




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Hypertension
3. Alpha Blockers (ABs)

Cardura Class Action Lawsuit

generic name
( -ate, ide, -ine, -sin)

Brand Name

Typ.
mg

Action/ Note

Side Effects

doxazosin mesylate

(generic available)

half-life= 22 hours

Cardura
Carduran

Duracin
Dosin
Doxazocine

1
2
4
8

Pfizer 

Dizziness, lightheadedness, excessive tiredness, swelling of the hands, feet, ankles, or lower legs, shortness of breath, dry mouth, drowsiness, muscle or joint pain or weakness, abnormal vision, runny nose, decreased sexual ability,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Rapid, pounding, or irregular heartbeat,
fainting,
painful erection of the penis that lasts for hours

phenoxybenzamine

half-life= 24 hours

Dibenzyline

10

-

Nasal congestion, dizziness, upset stomach, sexual dysfunction (difficulty ejaculating), dizziness

If you experience any of the following symptoms, call your doctor immediately:
Fainting,
fast heartbeat, vomiting

prazosin

(generic available)

half-life= 2-3 hours

Minipress
Vasoflex
Pressin
Hypovase

1
2
2.5
5

-

Dizziness, drowsiness, weakness, tiredness, headache, upset stomach,

If you experience any of the following symptoms, call your doctor immediately:
Difficulty breathing,
fast heartbeat,
irregular heartbeat,
chest pain, fainting

terazosin HCL

(generic available)

half-life= 12 hours

Hytrin
Zayasel

1
2
5
10

Dizziness, lightheadedness, weakness, tiredness, drowsiness, stuffed nose, back pain, upset stomach, decreased sexual ability, blurred vision, swelling of the hands, feet, ankles, or lower legs, pain, burning, or tingling in the hands or feet

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Rapid, pounding, or irregular heartbeat,
fainting,
painful erection of the penis that lasts for hours

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Hypertension
4. Angiotensin II Receptor
    
(ARBs)

generic name
( -sartan)

Brand Name

Typ.
mg

Action/ Note

Side Effects

candesartan

half-life= 9 hours

Atacand
Blopress

8
12.5
16
32

Astrazenica, Takeda
Sales Momentum
2003 - Gone!
2004 - Gone!
2005 - #183
2006 - #181
2007 - #179
2008 - #190
2009 - #199
2010 - Gone!
2011 - Gone!
2012 - Gone!

Dizziness, lightheadedness, congestion, cough, diarrhea, headache, muscle aches, back pain, fever, sore throat, runny nose,

If you experience any of the following symptoms, call your doctor immediately:
Swelling of the face, eyes, lips, tongue, arms, or legs,
difficulty breathing or swallowing,
fainting,
rash

irbesartan

half-life= 13 hours

Avapro

75
150
300

Bristol-Meyers Squibb 

Sales Momentum
2003 - #119
2004 - #113
2005 - #92
2006 - #96
2007 - #98
2008 - #94
2009 - #94
2010 - #91

2011 - Gone!
2012 - Gone!

Runny nose, sore throat, diarrhea, heartburn, excessive tiredness,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs,
hoarseness,
difficulty breathing or swallowing,
hives,
fainting

losartan

half-life= 2 hours

Cozaar

25
50
100

 Merck

Sales Momentum
2003 - #68
2004 - #74
2005 - #60
2006 - #56
2007 - #59
2008 - #54
2009 - #51
2010 - #119

2011 - Gone!
2012 - Gone!

Dizziness, runny nose, sore throat,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs,
hoarseness,
difficulty breathing or swallowing,
fainting

olmesartan

half-life= 13 hours

Benicar
Olmetec

5
20
40

Daiichi Sankyo
#73 Selling Drug 2006

Dizziness.

Seek medical attention right away if any of these SEVERE side effects occur when using Benicar:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; hoarseness); change in the amount of urine produced; chest pain; difficulty swallowing; fast, slow, or irregular heartbeat; muscle pain or cramps; symptoms of low blood pressure (eg, fainting, lightheadedness, severe dizziness).

telmisartan

half-life= 24 hours

Micardis

20
40
80

Boehringer
#58 Selling Drug 2006

-

valsartan

half-life= 6 hours

Diovan
Angiotan

80
160

Novartis
#9 Selling Drug 2006

Sales Momentum
2003 - #65
2004 - #57
2005 - #43
2006 - #39
2007 - #28
2008 - #25
2009 - #24
2010 - #18
2011 - #27
2012 - #24
2013 - #21

I quit taking this 2013 - too expensive. A generic is not available without HCTZ.

Dizziness, headache, excessive tiredness, diarrhea, stomach pain, back pain, joint pain,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, hoarseness,
difficulty breathing or swallowing,
fainting

Combo

Combination of 2 drugs - ARB and diuretic

irbesartan + HCTZ

Avalide

150-12.5
300-25

Bristol-Meyers Squibb 
#107 Selling Drug 2007

-

losartan + HCTZ

Hyzaar

50-12.5
100-12.5
100-25

-

-

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Hypertension
5. Diuretics

(Thiazides)
(Induce urination to reduce blood volume)

generic name
( -ide)

Brand Name

Typ.
mg

Action/ Note

Side Effects

amiloride

half-life= 6-9 hours

Midamor

5

Merck

-

bumetanide

(generic available)

half-life= 0.8 hours

Bumex

0.5
1
2

Roche

Muscle cramps, weakness, dizziness, faintness, thirst, upset stomach, vomiting, diarrhea,

If you have any of the following symptoms, call your doctor immediately:
Rapid, excessive weight loss,
sore throat with fever,
ringing in ears, loss of hearing,
unusual bleeding or bruising,
severe rash with peeling skin,
difficulty breathing or swallowing

chlortalidone
chlorthalidone
(generic available)

half-life= 40 hours

Thalitone

25
50

Monarch Pharma.

-

chlorothiazide

half-life= 45-60 hours

Diuril

250
500

Merck 

Erectile Disfunction,
Muscle weakness, dizziness, cramps, thirst, stomach pain, upset stomach, vomiting, diarrhea, loss of appetite, headache, hair loss,

If you experience any of the following symptoms, call your doctor immediately:
Sore throat with fever,
unusual bleeding or bruising,
severe skin rash with peeling skin,
difficulty breathing or swallowing

furosemide

(generic available)

half-life= 100 min.

Lasix

20
40
80

Aventis Pharma 

Muscle cramps, weakness, dizziness, confusion, thirst, upset stomach, vomiting, blurred vision, headache, restlessness, constipation,

If you have any of the following symptoms, call your doctor immediately:
Fever, sore throat,
ringing in the ears,
unusual bleeding or bruising,
loss of hearing,
severe rash with peeling skin,
difficulty breathing or swallowing,
rapid, excessive weight loss

hydrochloro-
thiazide (HCTZ)


(generic available)

half-life= 6-15 hours

HydroDIURIL

12.5
25
50

#18 Selling Drug 2004
Merck

4th Worst Heart Drug.
Erectile Disfunction,
Muscle weakness, dizziness, cramps, thirst, stomach pain, upset stomach, vomiting, diarrhea, loss of appetite, headache, hair loss,

If you experience any of the following symptoms, call your doctor immediately:
Sore throat with fever,
unusual bleeding or bruising,
severe skin rash with peeling skin,
difficulty breathing or swallowing
I quit this.

indapamide

(generic available)

half-life= 14-18 hours

Lozol

1.25
2.5

Sanofi

-

metolazone

(generic available)

half-life= 14 hours

Zaroxolyn

2.5
5
10

Rhône-Poulenc Rorer  

Muscle weakness, dizziness, cramps, thirst, stomach pain, upset stomach, vomiting, diarrhea, headache, hair loss,

If you experience any of the following symptoms, call your doctor immediately:
Sore throat with fever,
unusual bleeding or bruising,
severe skin rash with peeling skin,
difficulty breathing or swallowing

spironolactone

(generic available)

half-life= 1.3-2 hours

Aldactone

25
50
100

#56 Selling Drug 2004
Searle

Upset stomach, vomiting, diarrhea, stomach pain, frequent urination, dizziness, headache, enlarged or painful breasts, irregular menstrual periods, drowsiness,

If you experience any of the following symptoms, call your doctor immediately:
Muscle weakness or cramps,
rapid, excessive weight loss, fatigue,
slow or irregular heartbeat,
sore throat,
unusual bruising or bleeding,
yellowing of the skin or eyes, skin rash,
vomiting blood, fever, confusion

torsemide

(generic available)

half-life= 3.5 hours

Demadex

5
10
20
100

Roche Labs

-

triamterene

half-life= 1-2 hours

Dyrenium

50
100

GlaxoSmithKline 

Vomiting, dizziness, headache,

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
Muscle weakness or cramps,
slow or irregular heartbeat,
diarrhea, rash,
difficulty breathing or swallowing
upset stomach, extreme tiredness,
unusual bleeding or bruising,
lack of energy, loss of appetite,
pain in the upper right part of the stomach,
yellowing of the skin or eyes,
flu-like symptoms,
sore throat, severe dry mouth,
unusual bruising or bleeding

Combos

Combination of 2 diuretic drugs

amiloride
HCTZ
(generic available)

Moduretic

5-50

Merck

-

spironolactone
hydrochlorothiazide

Aldactazide

25-25
50-50

Pfizer
potassium sparing

-

triamterine hydrochlorothiazide
Combo

(generic available)

Dyazide

37.5-25
50-25
75-50

#24 Selling Drug 2004
GlaxoSmithKline

-

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Hypertension
6. Renin Blockers

DRI - Direct Renin Inhibitor ("reduces the effect of renin")

aliskiren

half-life= 24 hours

Tekturna

150
300

Novartis

Swelling, difficulty in breathing and swallowing, dizziness, flu-like symptoms, diarrhea, cough, tiredness.
The Novartis website describes Tekturna using a GRAPHIC, instead of the normal text. This is done so that the information cannot be indexed by search engines, because thay are attempting to hide something. Perhaps because it will kill your unborn baby. There is no other reason for them to present the information in this manner.

150

70

50

120

300 - 690



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2. Antiarrhythmia Drugs

generic name

Brand Name

Typ.
mg

Action/ Note

Side Effects

Antiarrhythmia Drugs
Class 1
Sodium Channel Blockers -
     Rhythm Control

 ( -ide, ine)

 -

 -

 -

 -

Class 1A

disopyramide- 1A

Norpace
Norpace CR

100
150

Rhythm-?

anti-cholinergenic effects
may cause Torsades de Pointes

procainamide- 1A

Procanbid
Pronestyl

500
1000

Rhythm-?

may cause med-induced SLE
may cause Torsades de Pointes

quinidine -   1A

Quinaglute
Quinidex

200
300

Rhythm-?
cinchona herb

may cause Torsades de Pointes

Class 1B

lidocaine -  1B

Xylocaine

ampule

-

seizures

phenytoin - 1B

Dilantin
Phenytek

100

-

med interactions

tocainide -  1B

Tonocard

400
600

-

tremor, pulmonary fibrosis

Class 1C

encainide -   1C

Enkaid

25
35

-

may worsen arrhythmias

flecainide -   1C

Tambocor

50
100
150

Rhythm-? no CAD, CHD

-

propafenone- 1C

Rytmonorm,
Rythmol

150
225
300

Rhythm-? no CAD, CHD

may worsen arrhythmias

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Antiarrhythmia Drugs
Class 2 (most used)
Beta Blockers - Rate Control -
     Stops transmission
(BBs)

 ( -olol)

 -

 -

 -

 -

acebutolol

Sectral

200
400

Dr. Reddy's Labs

-

atenolol

(generic available)

Tenormin

 25
50
100

#11 Selling Drug 2004
AstraZeneca

Dizziness, lightheadedness, tiredness, drowsiness, depression, upset stomach, diarrhea,

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Shortness of breath,
swelling of the hands, feet, ankles, or lower legs,
unusual weight gain, fainting

bisopropol

(generic available)

Concor


Zebeta

2.5
5
10

#193 Selling Drug 2006
Merck  

too-low blood pressure

carteolol

Cartrol

2.5
5

Abbott Labs

worse asthma symptoms

carvedilol

(generic available)

Coreg

3.125
6.25
12.5
25

Coreg Lawsuits

Glaxo Smith Kline
#70 Selling Drug 2006

Sales Momentum
2011 - >100
2012 - >100
2013 - >100

(They have me on carvedilol right now. I quit this crap - no effect on my BP.)

"If patients stop taking Coreg suddenly, they could have chest pain and/or a HEART ATTACK."

"Some COMMON side effects associated with Coreg CR include shortness of breath, a slow heartbeat, weight gain, fatigue, hypotension, dizziness, faintness, or runny nose/sore throat."
(capitalization mine)

ALL KINDS of intervening circumstances can cause you to "stop taking Coreg suddenly." Do you want to die, because of this? I DON'T LIKE any kind of medicine that causes dependance. Do you want to be a lifetime pharmaceutical addict? That's what THEY want!

esmolol 

Brevibloc

vial

Baxter

blocks heart w/ digitalis

betaxolol

Kerlone

10
20

Sanofi

-

labetalol

(generic available)

Trandate

100
200
300

Prometheus

-

metoprolol

(generic available)  

Lopressor

Toprol
Seloken

25
50
100

#42 Selling Drug 2004

#52 Selling Drug 2006

2nd Worst Heart Drug.
Dizziness or lightheadedness, tiredness, depression, upset stomach, dry mouth, stomach pain, gas or bloating, heartburn, constipation, rash or itching, cold hands and feet

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Shortness of breath, wheezing,
swelling of the hands, feet, ankles, or lower legs,
unusual weight gain, fainting,
rapid, pounding, or irregular heartbeat

Toprol XL

48
95

Astrazeneca

nadolol

(generic available)

Corgard

20
40
80

King Pharma.

-

penbutolol

Levatol

20

Schwarz Pharma.

-

pindolol

Visken

5

Novartis

-

propranolol

Inderol
InnoPran XL

10
20
40
60
80
120
160

Wyeth

Dizziness or lightheadedness, difficulty sleeping, excessive tiredness, upset stomach, vomiting, rash, diarrhea, constipation,

If you experience any of the following symptoms, call your doctor immediately:
Difficulty breathing,
sore throat,
unusual bleeding,
swelling of the feet or hands,
unusual weight gain,
chest pain,
slow, irregular heartbeat,

When they are throwing stuff at the wall, you can never be sure just what might KICK YOUR BUTT.

POISON - This stuff damn near killed me! They left out Crushing Chest Spasm, making breathing in or out EXTREMELY difficult. Can't walk, can't sit, can't lie down, can't sleep, can't breathe. AND, INSTANT PERMANENT ATRIAL FIBRILLATION. NO SINUS RHYTHM (NO PACEMAKER). FOR 12 YEARS NOW.

sotalol

(generic available)

Betapace

80
120
160

Berlex Labs.

plus K channel blocker

timolol

Blocadren

5
10
20

Merck

may cause Torsades de Pointes,
which frequently causes death

Combos

Combination of 2 drugs

bisopropol
HCTZ

Ziac

2.5-6.25
5-6.25
5-10
10-6.25

#95 Selling Drug 2004
Duramed Pharma.

too-low blood pressure

timolol/ HCTZ

Timolide

10-25

Merck

-

triamterene/ HCTZ

Dyazide

37.5-25
50-25

antikaliuretic agent/ diuretic

-

top of page

Antiarrhythmia Drugs
Class 3
Potassium Channel Blockers
   - Rhythm Control

 ( -ide, -ium, -lol, -one)

 -

 -

 -

 -

amiodarone

Cordarone (khella)

200
400

Wyeth

Rhythm-?
liver, thyroid, fibrosis

bretylium

Bretylol

vial

-

eye problems

dofetilide

Tikosyn

0.125
0.250
0.500

one pharmacy

may cause Torsades de Pointes

ibutilide

Corvert

vial

-

may cause Torsades de Pointes

sotalol

Betapace

80
120
160

works w/ purkinje

Rhythm-?

top of page

Antiarrhythmia Drugs
Class 4
Calcium Channel Blockers (CCBs)
   - Rate Control - Relaxes muscles

 ( -dil, -ipine, -mil, -zem)

 -

 -

 -

 -

amlodipine

Amlodin

Norvasc

2.5
5
10

Sales Momentum
2004 - #15
2005 - #10
2006 - #9

2007 - #52
2008 - GONE!

3rd Worst Heart Drug.
The author stopped taking amlodipine in 2014. HORRIBLE swelling of feet, ankles and lower leg.
The swelling greatly diminished 2 days after eliminating amlodipine.

amlodipine
benazepril
Combo

Lotrel

2,5-10
5-10
5-20
5-40
10-20
10-40

#74 Selling Drug 2006

-

bepridil

Vascor

200
300

-

-

diltiazem

(generic available)


(I love this stuff - author)

Cardizem

30
60
90
120
180
240
300
360

#25 Selling Drug 2004
Aventis

Dizziness or lightheadedness, flushing (feeling of warmth), headache, excessive tiredness, slower heartbeat, upset stomach, loss of appetite, vomiting, diarrhea, constipation, stomach pain, dry mouth, difficulty falling asleep or staying asleep,

If you experience any of the following symptoms, call your doctor immediately:
Swelling of the face, eyes, lips, tongue, arms, or legs,
difficulty breathing or swallowing,
fainting, rash,
yellowing of the skin or eyes, fever,
increase in frequency or severity of chest pain (angina)

Cartia XT

#45 Selling Drug 2004
Douglas

Dilacor

Benzo-thiaz-epine

Taztia XT

Tiazac

felodipine

Plendil

2.5
5
10

 -

-

isradipine

DynaCirc

2.5
5
10

 -

-

nicardipine

Cardene

20
30

 -

-

nifedipine 

Adalat

10
20
30
60
90

 Bayer
#128 Selling Drug 2006

-

Procardia

 -

-

nisoldipine

Sular

20
30
40

 -

-

verapamil

(generic available)

Calan

80
100
120
180
200
240
360

Searle

Constipation, dizziness or lightheadedness, headache, upset stomach, heartburn, excessive tiredness, flushing (feeling of warmth), slow heartbeat, vivid, unusual dreams,

If you experience any of the following symptoms, call your doctor immediately:
Swelling of the face, eyes, lips, tongue, arms, or legs
difficulty breathing or swallowing,
fainting, rash,
yellowing of the skin or eyes, fever,
increase in frequency or severity of chest pain (angina)

Covera

Phenyl-alky-amine

Isopten

Phenyl-alky-amine

Verelan

Phenyl-alky-amine

150

70

50

150

270 - 690

top of page

3. Cholesterol Lowering
    - Anti-lipemic

Statin Class Action Lawsuits

generic name
(-statin)

Brand Name

Typ.
mg

Action/ Note

Side Effects

STATINS

-

atorvastatin

Lipitor

10
20
40
80

Pfizer

Sales Momentum
2003 - #1
2004 - #1
2005 - #1
2006 - #1
2007 - #1
2008 - #1
2009 - #1
2010 - #2
2011 - #1
2012 - #31
2013 - >100

After being #1 forever,
Lipitor took a dive in 2012,
and went into oblivion in 2013.

cerivastatin

Baycol

-

Recalled 2001

Baycol Class Action Lawsuits

cholestyramine

Questran

powder

-

-

ezetimibe (Zetia) and simvastatin (Zocor)
Combo

Vytorin

10-10
10-20
10-40
10-80

Sales Momentum
2005 - #49
2006 - #22
2007 - #12
2008 - #18
2009 - #29
2010 - #33
2011 - #53
2012 - #71
2013 - #70

Waning popularity

fluvastatin

Lescol

20
40
80

Novartis
#151 Selling Drug 2006

-

lovastatin

(generic available)

Mevacor

10
20
40

Merck

Constipation

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
Muscle pain, tenderness, or weakness,
lack of energy or fever,
yellowing of the skin or eyes

pravastatin

(generic available)

Mevalotin
Pravachol

10
20
40

Sales Momentum
2011 - >100
2012 - >100
2013 - >100

Fallen into disfavor

rosuvastatin

Crestor

5
10
20
40

AstraZenica

Sales Momentum
2003 -Gone!
2004 - #88
2005 - #51
2006 - #37
2007 - #23
2008 - #17
2009 - #14
2010 - #9

2011 - #8
2012 - #3
2013 - #4

Great sales record

simvastatin

Zocor

10
20
40
80

Merck

Sales Momentum
2003 - #2
2004 - #2
2005 - #4
2006 - #8

2007 - Gone!
2008 - Gone!
2009 - Gone!
2010 - Gone!
2011 - Gone!
2012 - Gone!
2013 - Gone!

Fallen into disfavor

.
NON-STATINS

-

colestipol

Colestid

1

-

Chest pain, angina, and tachycardia have been reported.

ezetimibe

Zetia

10

Merck

Sales Momentum
2003 - #126
2004 - #68
2005 - #39
2006 - #32
2007 - #21
2008 - #30
2009 - #33
2010 - #31
2011 - #40
2012 - #39
2013 - #29

Severe allergic reaction
Difficulty breathing
Abdominal pain, diarrhea, tiredness

fenofibrate

Tricor
Lipanthyl

54
134
200

Abbott Labs

Sales Momentum
2003 - #79
2004 - #63
2005 - #45
2006 - #40
2007 - #30
2008 - #26
2009 - #26
2010 - #29
2011 - #41
2012 - #54
2013 - Gone!

Gone!

niacin

Niaspan

500

#70 Selling Drug 2007
KOS Pharma.

-

top of page

4. Blood Thinners -
    Anticoagulants

Blood Thinners

(to prevent stroke)

generic name
( -in)

Brand Name

Typ.
mg

Action/ Note

Side Effects

aspirin

Bayer

81
325

-

Increased bleeding risk
Easy bruising
sodium retention

apixaban

Eliquis

2.5 - BID
5 - BID

new 2013

Increased bleeding risk

aprotinin

Trasylol

-

hospital use
BANNED from worldwide market in 2007

Increased bleeding risk
Trasylol Lawsuits

clopidogrel

Plavix

75
300

Sales Momentum
2011 - #2
2012 - #17
2013 - >100

Increased bleeding risk
Plavix Lawsuits
Stomach bleeding

dabigatran etexilate

Pradaxa

75
150

Sales Momentum
2011 - >100
2012 - #78
2013 - #73

Increased bleeding risk
Pradaxa Lawsuits
TV Atty. Bob Goldwater accepts Pradaxa cases linked to serious side effects including death.

enoxaparin sodium

Lovenox

-

Sales Momentum
2005 - #77
2006 - #58
2007 - #53
2008 - #40
2009 - #31
2010 - #41
2011 - #51
2012 - Gone!
2013 - Gone!

Straight downhill

heparin

Calciparine

-

hospital use

Heparin Lawsuits

rivaroxaban

Xarelto

-

clotting protein blocker
new 2011 - Bayer
for a-fib patients

Increased bleeding risk
Xarelto Lawsuits

warfarin

(generic available)

Coumadin

1
2
2.5
3
4
5
6
7.5
10

Bristol-Myers Squibb


If you receive too little warfarin, you can get a blood clot, and suffer a stroke. If you receive too much warfarin, you can bleed internally, such as stomach bleeding at best, or brain hemorrhage at worst.

I replaced this with aspirin.
Increased bleeding risk
Coumadin Lawsuits
Headache, upset stomach, diarrhea, fever, skin rash,

If you experience any of the following symptoms, call your doctor immediately:
Unusual bleeding or bruising,
black or bloody stools,
blood in the urine, tiredness,
unexplained fever, chills,
sore throat,
stomach pain

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5. Rate Control Drugs

Digitalis Preparations

(Pulse Rate Control)

generic name
( -oxin)

Brand Name

Typ.
mg

Action/ Note

Side Effects

digoxin
(foxglove herb)

(generic available)

Lanoxin

0.125

-

Loss of appetite
bad taste in the mouth
nausea or vomiting
impaired kidney function
headaches
skipped heartbeats
rapid breathing

Digitran

0.25

-

digitoxin

Crystodigin
Tardigal
Unidigin

0.10
0.20

-

-

top of page

6. Vasodilators

Vasodilators

(Expand blood vessels)

generic name

Brand Name

Typ.
mg

Action/ Note

Side Effects

hydralazine

(generic available)

Apresoline

10
25
50
100

Novartis

Flushing (feeling of warmth), headache, upset stomach, vomiting, loss of appetite, diarrhea, constipation, eye tearing, stuffy nose, rash,

If you experience any of the following symptoms, call your doctor immediately:
Fainting, joint or muscle pain,
unexplained fever, rapid heartbeat,
chest pain, swollen ankles or feet,
numbing or tingling in hands or feet

isosorbide dinitrate

(generic available)

Isordil

5
10
20
30
40

Wyeth

Headache, rash, dizziness, upset stomach, headache, flushing (feeling of warmth),

If you experience any of the following symptoms, call your doctor immediately:
Blurred vision, dry mouth, chest pain,
fainting

isosorbide mononitrate

(generic available)

Imdur
Ismo

10
30
60
120

ESP Pharma.
Schering

-

nitroglycerin

(generic available)

Nitrobid
Nitrostat

2.5
6.5
9

Aventis
Pfizer

Headache, rash, dizziness, upset stomach, flushing (feeling of warmth),

If you experience any of the following symptoms, call your doctor immediately:
Blurred vision,
dry mouth, chest pain, fainting

nitroglycerin

(generic available)

NitroQuick

0.3
0.4
0.6

Phizer

-

top of page

7. Non-heart Drugs That
Cause Heart Attacks

celecoxib

Celebrex

-

Celebrex Heart Attack

Heart Attack
Stroke
Vioxx Class Action Lawsuits
Full List

rofecoxib

Vioxx

-

Recalled 2004

valdecoxib

Bextra

-

Recalled 2005

150

70

50

150

270 - 690



top of page

Top U.S. Heart Drug Sales List -
Comparison Chart
2008 through 2013

.
Sales Rank by Year
Heart Drugs
Listed by
2013 Sales

  Primary Use

Company

.
Notes

TOP 200 DRUGS
.
TOP 100 DRUGS
'08
'09
'10
'11
'12
'13
17
14
9
8
3
4

Crestor

cholesterol

AstraZeneca

Rapid growth

25
24
18
27
24
21

Diovan

hypertension - ARB

Novartis

Steady growth

>200

>200

>200

20
22
22

Epogen

anemia

Amgen

Resurrection!

30
33
31
40
39
29

Zetia

cholesterol

Merck

Steady growth

>200

34
30
34

enoxaparin

anticoagulant

Winthrop

generic

56
48
45
46
59
47

Niaspan

cholesterol (niacin)

Kos Pharma.

Steady growth

118
142
174
45
57
57

Procrit

anemia

J & J

Resurrection!

>200

67
65
61

metoprolol

beta blocker

various

generic

18
29
33
53
71
70

Vytorin

cholesterol

Merck

Fading fast

>100

78
73

Pradaxa

anticoagulant

Boehringer-Ingelheim

Doomed

86
67
57
91
87
76

Benicar

hypertension - ARB

Sankyo Pharma.

Steady growth

>200

>200

>200

48
70
80

Aranesp

anemia

Amgen

Resurrection!

>200

96
21
93

atorvastatin

cholesterol

Apotex

generic

>100

98

hctz/valsartan

hypertension - ARB

-

generic

>100

99

Xarelto

anticoagulant

Janssen

Doomed

1
1
2
1
31

>100

Lipitor

cholesterol

Pfizer

Lipitor is GONE!

3
3
3
2
17

>100

Plavix

anticoagulant

Bristol-Myers Squibb

Big seller - big drop

29
25
23
32
45

>100

Diovan HCT

Combo - AIIRA + HCTZ

Novartis

Topped out

26
26
29
41
54

>100

Tricor

cholesterol

Abbott Labs

40
31
41
51

>100

>100

Lovenox

anticoagulant

Sanofi-Aventis

2008
2009
2010
2011
2012
2013

74
63
61

>100

>100

>100

Benicar HCT

Combo - ARB + HCTZ

Sankyo Pharma.

Topped out

94
94
91

>100

>100

>100

Avapro

hypertension - AIIRA

Bristol-Myers Squibb

102
106
102

>100

>100

>100

Avalide

Combo - AIIRA + HCTZ

Bristol-Myers Squibb

>200

110
106

>100

>100

>100

Lotrel

Combo - ACE In. + CCB

Novartis

154
132
108

>100

>100

>100

Welchol

cholesterol

Sankyo Pharma.

54
51
119

>100

>100

>100

Cozaar

hypertension - AIIRA

Merck

>200

109
121

>100

>100

>100

Caduet

Combo - chol. + CCB

Pfizer

25
130
128

>100

>100

>100

Coreg CR

hypertension - BB

GlaxoSmithKline

182
160
133

>100

>100

>100

Micardis

hypertension - AIIRA

Boehringer-Ingelheim

71
66
150

>100

>100

>100

Hyzaar

Combo - losartan + HCTZ

Merck

157
172

>200

>100

>100

>100

Catapres-TTS

hypertension - AA

Boehringer-Ingelheim

These drugs have fallen off the map.
Once thought good, where are they now?

190
199

>200

>100

>100

>100

Atacand

hypertension - AIIRA

Astrazeneca

165

>200

>200

>100

>100

>100

Altace

hypertension - ACE In.

Wyeth

>200

>200

>200

>100

>100

>100

Coreg

carvedilol - Beta blocker

GlaxoSmithKline

>200

137

>200

>100

>100

>100

Toprol XL

hypertension - BB

Astrazeneca

>200

>200

>200

>100

>100

>100

Norvasc

hypertension - CCB

AKA amlodipine

>200

>200

>200

>100

>100

>100

Coumadin Tabs

anticoagulant

Bristol-Myers Squibb

>200

>200

>200

>100

>100

>100

Lescol XL

cholesterol

Abbott Labs

>200

>200

>200

>100

>100

>100

Zocor

cholesterol

Merck

>200

>200

>200

>100

>100

>100

Pravachol

cholesterol

Bristol-Myers Squibb

>200

>200

>200

>100

>100

>100

Lisinopril

hypertension - ACE In.

Teva Pharma.

Wicked cough

>200

>200

>200

>100

>100

>100

Lotensin

hypertension - ACE In.

Novartis

Cough

>200

>200

>200

>100

>100

>100

Monopril

hypertension - ACE In.

Bristol-Myers Squibb

Cough

2008
2009
2010
2011
2012
2013

-

-

  Red = Sales drop from previous year
  Green = Sales increase from previous year
  >200 = Drugs that have shrunk in sales

-

40

40

40

40

40

40

80

160 - 750

120

150



top of page

Vaughn's Other
PRESCRIPTION DRUG Related Pages

* Painkiller Comparison

*
Prescrip. Blood Thinners

*
Prescrip. Drug Classes

*
Prescrip. Drug Lawsuits

*
Prescrip. Drug Risks

*
Prescrip. Drug Sales

*
Prescrip. Drug Side Effects

*
Prescrip. Drug TV Ads

*
Prescrip. Drug Warnings

*
Prescrip. Heart Drugs

*
Rejected Prescrip. Drugs

*
Unapproved Prescrip. Drugs
.




DISCLAIMER
Top Selling Drugs data from drugs.com.
The author has no medical training. No advice is intended.
Although the author has tried to be as accurate as possible, errors, mis-statements and misspellings are possible.

Use this heart medicine guide to begin your in-depth study of the medications that concern you.
Consult your doctor for personal advice. I could not find a simple heart drug list. So, I compiled the one above, to help myself understand heart treatment alternatives. I hope that it helps you.

top of page



Vaughn Aubuchon Author Bio

Vaughn's Summaries
©2004-2016 Vaughn Aubuchon
www.vaughns-1-pagers.com
All Rights Reserved
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This Vaughns Prescription Heart Drugs
page was partially updated on 2016-05-06.